Here is some Information to get you started and setup for Folding.

Things to consider.
Running a folding client or multiple folding clients can be stressful on your hardware.
It can also cause your hardware to create more heat then usual. It is recommended that you test your systems ability to coop with that added stress and heat appropriately.
It is also recommended that you continue to monitor your systems health.
The Team
So You made the decision to do it. now, where to start?
First You need to know which team You would like to support in you effort.
Next you need to find that teams ID number, in our case that is ID# 53269.
You can find this information at FAH's Team Statistics page.
Type in the team name, the fields populate with the current statistics and the Team ID.

The Client
Next you need to decide what client(s) is appropaite for you and where to get them.
First of all, there are two typs of clients. The Console Client and the Systray Client.

The Console Client will have a installer package plus a few windows for configuration as
well as a display window to show you and keep you updated on the current folding
project and status.

The Systray Client is far less fancy and makes good use of the extra processing cycles
to add performance. I would recommend this client for the little bit more advanced user.

The Platform
Folding@Home can make use of your CPU or your GPU/ Video Card.
Clients for both are available and can be run at the same time.
Because of GPU's very high (FLOPS) Floating Point Operation count
they are very good performers for Folding and Stanford has done a great job optimizing the clients.
For multi CPU packages there is also a SMP client. Resources CPU Client SMP Client GPU Client